Konwersatoria odbywają się o godz. 16:30 poprzez aplikację Webex (recording, privacy) i prowadzone są w języku angielskim.
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Kontakt:
Maksymilian Szymczak
Konwersatoria odbywają się o godz. 16:30 poprzez aplikację Webex (recording, privacy) i prowadzone są w języku angielskim.
Aby otrzymywać informacje o comiesięcznych konwersatoriach zarejestruj się pod linkiem.
Kontakt:
Maksymilian Szymczak
Glycosylation is a co-translational and post-translational attachment of sugar moieties (glycans) to proteins. This complex process affects glycoprotein structure, proper folding, and its function. Glycans are essential for protein interactions on a cell surface, enable proper cell signalization and recognition, and are the result of both genetic and environmental factors. Aberrant glycosylation patterns have been associated with different diseases and have a high potential as diagnostic and prognostic disease biomarkers. To study glycosylation patterns of glycoproteins in large-scale human population, epidemiological and clinical studies, a lot of effort has been put into the development of robust, accurate, and fast methods for glycan analysis in hundreds and thousands of samples (so-called high-throughput methods).
This lecture will cover a brief introduction on protein glycosylation, give an overview of currently used approaches for high-throughput glycosylation analysis with a focus on challenges, highlight several applications, and provide some future perspectives.