Pursuant to § 7 sections 1 and 3 of Resolution No. 68/IX/2020 of the Senate of the Jagiellonian University of 30 September 2020 on: the rules of recruitment for the Doctoral School of Exact and Natural Sciences at the Jagiellonian University in the academic year 2020/2021, the Director of the Doctoral School of Exact and Natural Sciences announces a competition for 1 doctoral student/s with a scholarship financed from the research project (“Implementation PhD”) funds as part of the PhD study programme Biology.
The project manager, dr hab. Małgorzata Lenartowicz, prof. UJ offers an opportunity to complete the doctorates in the following area: "SEL120, dual inhibitor of CDK8/CDK19 in the treatment of acute myeloid leukemia: patients stratification and finding a partner for combination therapy".
After the interviews and the evaluation of the candidates, the Chairman of the committee presents a report to the Director containing a list of candidates recommended for admission to the school as part of the research project.
Schedule of the competition:
- Opening of the competition: 23.08.2021
- Application submission deadline: 30.08.2021
- Entrance exams: 2-3.09.2021
- Announcement of results: 07.09.2021
- Enrolment: 08.09.2021
Detailed terms and procedures of admission.
Project description
Employer's declaration of employing a doctoral student
Candidate's profile:
- Higher education (Master's degree in the field of Biotechnology)
- Minimum three years of experience in a company from the biotechnology sector, in work related to cancer biology
- The ability to plan research experiments on the analysis of human neoplasms
- Experience in working with neoplasms of the hematopoietic system, especially in acute myeloid leukemia (AML), especially in designing and conducting in vitro experiments in a cell culture model (including primary) with the use of cyclin-dependent small molecule kinase inhibitors. Experience in working with human xenografts from patients
- Practical knowledge of laboratory methods: flow cytometry, electrophoresis, Western blot, immunoprecipitation, CETSA, fractionation, ELISA, QPCR, cell culture management (cell lines, patient xenografts), cell viability tests, synergy tests, qPCR
- Practical ability to search databases on the human genome and mutations, and the ability to analyze data obtained in transcriptomic reactions
- Documented scientific achievements including publications and participation in scientific conferences
- Knowledge of English at the minimum level of B
- An additional advantage will be:
- Practical ability to analyze synergy with the use of specialized programs: Combenefit and CompuSyn, equipment operation: BD LSR Fortessa flow cytometer (Diva software), Tecan D300 dispenser.
