Mrs. Weronika Szukała, PhD student at our Doctoral School, studying at the Faculty of Biochemistry, Biophysics and Biotechnology at the Jagiellonian University, obtained a grant - Preludium 19 for the amount of PLN 200 760. Congratulations!
Mrs. Weronika will explore the topic of "MCPIP1 in the regulation of skin homeostasis" – we invite you to read the short description of the research.
MCPIP1, as a negative regulator of inflammation, also plays an important role in the physiology and pathophysiology of the epidermis. It is known that the level of MCPIP1 protein is increased in the skin of people suffering from psoriasis. The aim of this project is to test the role of MCPIP1 in the interaction of skin cells (keratinocytes) with cells of the immune system (myeloid line) during the development of psoriasis. To reach this aim, we will use genetically modified mice with depletion of MCPIP1 expression in keratinocytes and myeloid cells. After chemical induction of psoriasis, skin morphology and function as well as immune response will be analyzed.
Good luck in your research!