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Involvement of gasotransmitter systems in the brain response to seizure activity in animal models of epilepsy (prof. dr hab. Krzysztof Janeczko)

Involvement of gasotransmitter systems in the brain response to seizure activity in animal models of epilepsy (prof. dr hab. Krzysztof Janeczko)

Pursuant to § 7 sections 1 and 3 of Resolution No. 91/IX/2021 of the Senate of the Jagiellonian University of 29 September 2021 on the rules of recruitment for the Doctoral School of Exact and Natural Sciences at the Jagiellonian University in the academic year 2022/2023, the Director of the Doctoral School of Exact and Natural Sciences announces a competition for 1 doctoral student with a scholarship financed from the research project funds as part of the 4-year PhD programme in Biology.

Within the NCN-funded project entitled a commission set up by the Head of  the Doctoral School will conduct recruitment for the PhD Programme in Biology. The project manager, Prof. dr hab. Krzysztof Janeczko, offers an opportunity to complete the doctorate in the following area: Involvement of gasotransmitter systems in the brain response to seizure activity in animal models of epilepsy.

 

Please upload your application into the Online Application System (open from 25.07.2022 r).

Schedule of the competition:

  • Start of registration: 25.07 2022
  • End of registration: 25.08.2022.
  • Entrance exams: 1-2.09.2022 r.
  • Announcement of results: 06.09.2022 r.
  • Enrolment: 08-13.09.2022 r.

Detailed terms and procedures of admission - tailored to the specific PhD study programme according to the current Recruitment rules for the specific academic year. In academic year 2022/2023 in accordance with Resolution No 91/IX/2021 of the Senate of the Jagiellonian University of 29 September 2021 concerning: the rules of enrolment to the Doctoral School of Exact and Natural Sciences at the Jagiellonian University in the academic year 2022/2023.

For PRELUDIUM BIS 3 also in accordance with the criteria specified in Annex 2 to the Terms and Conditions of Awarding Funds for the Implementation of Tasks Funded by the National Science Centre under research projects, annexed to the Resolution of the Council of the NCN no 79/2021 of 9 September 2021 (point 2.1.3).

Summary

In clinical conditions, the temporal epilepsy is manifested by spontaneous, repeated seizures leading to inflammatory changes, neuronal degeneration and increasing seizure susceptibility resulting from imbalance between excitatory and inhibitory “classical” neurotransmitters. This concept was significantly modified after subsequent discoveries of intercellular interactions via gaseous particles: nitric oxide, carbon monoxide and hydrogen sulfide. However, very little is known about possible roles of the gasotransmitters in epileptogenesis and its destroying or protecting influences on the brain.  Therefore, we will focus on the still insufficiently defined, integrated spatio-temporal pattern of reactive variations in the enzyme gasotransmitter-producing systems and neurodegenerative changes occurring in the brain after seizures in animal models of epilepsy.

Required documents:

  • curriculum vitae (CV) including scientific achievements;
  • motivation letter explaining how interests and research experience make the applicant a suitable candidate for this project;
  • letter of reference for a candidate from a scientist with at least a postdoctoral degree or an employee of a foreign research institution with significant achievements in biological sciences;
  • statement of support from a researcher holding the academic title of professor or the academic degree of doctor habilitated employed in the unit in which the study programme is implemented and who is the project manager about the possibility of undertaking scientific cooperation in a specific scope in the event of the candidate being accepted for the study programme at the Doctoral Schoolof Science and Natural Sciences (form to be downloaded from the website);
  • holds or will have a master's degree in natural sciences, or at the latest on the day of enrollment in the doctoral school,
  • list of grades for courses completed during the studies.
Each document issued in a language other than Polish or English must be accompanied by a certified translation into Polish or English.

Candidate profile:

  • master's degree in biology or neurobiology;
  • knowledge of the basic principles of laboratory work, especially with biological material;
  • experience in the laboratory use of animal models (rodents) with appropriate, documented authorizations;
  • experience in application of histological techniques, especially immunohistochemistry;
  • strong motivation and commitment to implementation of the project;
  • full availability during the research project implementation;
  • willingness and personal predisposition to cooperate with a team;
  • good written and oral communication skills in English.
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