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DNA topoisomerase biology (Supervisor: prof. dr hab. J. Heddle)

DNA topoisomerase biology (Supervisor: prof. dr hab. J. Heddle)

Pursuant to § 7 sections 1 and 3 of Resolution No. 91/IX/2021 of the Senate of the Jagiellonian University of 29 September 2021 on the rules of recruitment for the Doctoral School of Exact and Natural Sciences at the Jagiellonian University in the academic year 2022/2023, the Director of the Doctoral School of Exact and Natural Sciences announces a competition for 1 doctoral student with a scholarship financed from the research project funds as part of the 3-year PhD study programme Biomedical Sciences.
Within the NCN-funded project entitled "Structural Basis Of Transmissible Fluoroquinolone Resistance", a commission set up at the School will conduct recruitment for the 3-year PhD study programme Biomedical Sciences in the academic year 2022/2023.
 
The project manager, Prof. dr hab. Jonatan Heddle offers an opportunity to complete the doctorate in the following area: DNA topoisomerase biology.
 
After the interviews and the evaluation of the candidates, the Chairman of the committee presents a report to the Director containing a list of candidates recommended for admission to the school as part of the research project.


Schedule of the competition:

  • Opening of the competition: 01.09.2022
  • Application submission deadline: 09.09.2022, noon
  • Entrance exams: 20-21.09.2022
  • Committee meeting - no later than: 21.09.2022
  • Exam results: 26.09.2022
  • Entries to the Doctoral School: 27-29.09.2022
  • Entries to the Doctoral School - reserve list: 30.09.2022

Detailed terms and procedures of admission

Application documents

  • Motivation letter, explaining how the applicant’s background and research interests make them a suitable candidate for the position;
  • Curriculum vitae (CV) with particular emphasis on scientific achievements;
  • A copy of degree certificates (master's degree, master of engineer, equivalent);
  • Names of at least two referees (including a former supervisor) who can be contacted if needed (their contact details and academic title) and at least one reference letter written for the candidate by a researcher holding at least the academic degree of doktor habilitowany (post-doctoral degree) or being an employee of a foreign higher education institution or research institution who has a substantial track record in life sciences
  • Documents demonstrating the scientific achievements listed in the curriculum vitae, e.g. first page of the article if not easily searched
  • Transcript of grades: diploma supplement or the official transcript of grades, or another document listing completed courses and grades. Information about the grading scale must be included
  • the original application and a photograph (35 mm × 45 mm; photo without headgear on a light background digital version to upload into the Online Application System)

Any document submitted in a language other than English must be accompanied by a certified translation into English.

The ideal candidate should fulfil the following criteria:

  • Possess master's, master of an engineer or equivalent degree in molecular biology, structural biology, biochemistry or related areas.
  • Be motivated to study biochemistry and structural biology
  • Have strong work commitment and the ability for independent work
  • Have excellent written and oral communication skills in English
  • Have good skills in work management and experimental record keeping.
  • Able to work across disciplines and be willing to gain expertise in new areas.
  • Able to work as a part of the team and with international collaborators

Please send your application documents to the project manager, Prof. dr hab. Jonathan Heddle at jonathan.heddle@uj.edu.pl and upload them into the Online Application System.

The Bionanoscience and Biochemistry laboratory is recruiting a doctoral student for a fully-funded position with a duration of up to three years. The successful candidate will work on an NCN-funded project to uncover the mechanisms of transmissible fluoroquinolone resistance in Mycobacterium tuberculosis. While working on the project, you will use cryo-electron microscopy to study the interactions of fluoroquinolone resistance protein MfpA with Mycobacterial DNA gyrase. The project offers an opportunity to carry out basic molecular biology research (DNA topoisomerase biology) with a real-world impact (antimicrobial drug resistance). 
You will learn relevant techniques of protein production and structural biology techniques, particularly cryo-EM. You will also have the opportunity to participate in silico drug design, screening and activity testing.
 
More information about the Bionanoscience and Biochemistry laboratory is available under the link.

Documents required for enrollment:

  • for inspection: identity card (passport in case of foreigners);
  • a photocopy and the original for inspection:
  • a) a diploma certifying the holding of a degree of Master, Master Engineer or equivalent in a field of study from among those indicated in the detailed conditions of recruitment, or
  • b) a diploma of completion of studies abroad, giving the right to enrol in a course of doctoral  studies in the issuing country or recognised as equivalent to the appropriate Polish diploma confirming the qualifications of the second degree;
  • if the candidate has not yet been issued such a diploma by the deadline for admission,
  • he/she shall submit a certificate of completion of such studies and a written undertaking to provide the diploma of higher education entitling to enrol in a course of doctoral studies within the prescribed deadline;
  • for inspection: identity document (passport in case of foreigners);
  • originals of all other documents provided at the registration stage in the form of a scan.
In the event of exposure to harmful, noxious or hazardous factors, the applicant will, at the time of registration, be referred for a medical examination by an occupational medicine physician. The candidate shall be obliged to deliver, within the time limit set by the programme manager, a medical certificate confirming the absence of contraindications to take up education.
 

Higher education diplomas awarded abroad should:

  1. bear an apostille clause if the issuing country is covered by the Convention abolishing the requirement legalisation for foreign public documents, done at The Hague on 5 October 1961 (Journal of Laws of 2005, No. 112, item 938) or
  2. be subjected to legalisation, in other cases.

Any document submitted in a language other than English must be accompanied by a certified translation into English.

Insurance:

Each doctoral student, including a foreigner, admitted to the doctoral school is obligatorily subject to health insurance if he/she is not covered by such insurance on other grounds (e.g. employment relationship, contract of mandate, business activity, insured as a family member under 26 years of age, as the spouse of an insured person). The health insurance contribution is paid by the Jagiellonian University and is financed from the State budget. In addition, a doctoral student receiving a doctoral scholarship is subject to compulsory retirement and disability insurance and accident insurance

IMPORTANT:

A person admitted to the doctoral school begins education and acquires doctoral student rights upon taking the oath. The Department of Personal Affairs reports each doctoral student admitted to the School to compulsory health and social insurance at the commencement of education, i.e. from 1 October at the earliest. Until that time foreign candidates are obliged to cover the costs of insurance for the time of travel, treatment, etc. individually
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